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Timbuk2 Bags/Hayes Valley

Pros: Indestructible cool looking messenger, play or travel bags
Cons: Only one brick and mortar store to check out variety and feel
Best For: Looking like a local

Founded by a former bike messenger, Timbuk2 bags are quintessential San Francisco. They have been manufactured in the city since 1989, and mostly people order online, where you can design your own messenger bag. Check out the TSA compliant laptop bags.
506 Hayes St (at Octavia)
San Francisco, 94102
Store Hours: Mon 12-6pm, Tues-Fri 11am-7pm, Sat 10am-7pm, Sun 11am-6pm